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When You Need More
Blood Sugar Control


Even if you've been doing everything you can to manage your diabetes, you may still need more control over your blood sugar. This doesn't mean that you haven't been doing everything right. Diabetes changes over time. The most important thing about managing diabetes is finding the diabetes care plan that works best for you.

What is basal-bolus insulin therapy?

In the body of a person without diabetes, insulin works to control blood sugar:

  • Insulin is released in steady amounts, day and night, to help control blood sugar between meals and during sleep
  • Insulin is also released in bursts to help control blood sugar from meals

Someone with diabetes may need help controlling blood sugar in both ways:

  • Insulin therapy that helps you control blood sugar between meals and during sleep is called long-acting or basal insulin
  • Insulin therapy that helps you control blood sugar from meals is called bolus insulin , meaning itʼs released in a burst. NovoLog® is a bolus insulin

When you need more control over your blood sugar levels, your doctor may suggest basal-bolus therapy, also called intensive insulin therapy. Basal-bolus therapy is recommended for people with type 1 diabetes. It may also be recommended for people with type 2 diabetes who need better blood sugar control.

People on basal-bolus therapy monitor their blood sugar levels closely and take insulin doses often. The goal of this kind of insulin therapy is to mimic the way blood sugar is controlled naturally.

Your basal-bolus therapy care plan

In addition to changes in diet and exercise, your basal-bolus therapy care plan will include taking a long-acting basal insulin dose along with a dose of NovoLog® at mealtime up to 3 times daily.

This combination imitates the body's natural insulin response and has been shown to help people with diabetes lower their A1C levels.

It will also be important to:

  • Monitor your blood sugar levels often
  • Follow your meal and exercise plans closely
  • Communicate with your diabetes care team regularly

Basal-bolus therapy is recommended for appropriate patients by the American Diabetes Association (ADA) and the American Association of Clinical Endocrinologists (AACE).

For more information on intensive insulin therapy, talk with your diabetes care team. Together, you can decide if it is right for you. For help talking to your doctor, try using our Doctor Discussion Guide.

Indications and Usage

What is NovoLog® (insulin aspart [rDNA origin] injection)?

NovoLog® is a man-made insulin used to control high blood sugar in adults and children with diabetes mellitus.

Important Safety Information

Who should not use NovoLog®?

Do not use NovoLog® if your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients.

What should I tell my health care provider before taking NovoLog®?

About all of your medical conditions, including liver, kidney, or heart problems.
If you are pregnant, breastfeeding, or plan to do either.
About all prescription and nonprescription medicines you take, including supplements, as your dose may need to change.

How should I take NovoLog®?

Eat a meal within 5 to 10 minutes after using NovoLog®, a fast-acting insulin, to avoid low blood sugar. Do not inject NovoLog® if you do not plan to eat right after your injection or bolus pump infusion.
Do not mix NovoLog® with any other insulin when used in a pump or with any insulin other than NPH when used with injections by syringe.
Do not change your dose or type of insulin unless you are told to by your health care provider.
Do not share needles, insulin pens, or syringes.
Check your blood sugar levels as directed by your health care provider.

What should I consider while using NovoLog®?

Alcohol, including beer and wine, may affect your blood sugar.
Be careful when driving a car or operating machinery. You may have difficulty concentrating or reacting if you have low blood sugar. Talk to your health care provider if you often have low blood sugar or no warning signs of low blood sugar.

What are the possible side effects of NovoLog®?

Low blood sugar, including when too much is taken. Some symptoms include sweating, shakiness, confusion, and headache. Severe low blood sugar can cause unconsciousness, seizures, and death.
Serious allergic reactions may occur. Get medical help right away, if you develop a rash over your whole body, have trouble breathing, a fast heartbeat, or sweating.
Other side effects include injection site reactions (like redness, swelling, and itching), skin thickening or pits at the injection site, swelling of your hands and feet, if taken with thiazolidinediones (TZDs) possible heart failure, vision changes, low potassium in your blood, and weight gain.

For more information, please click here for complete NovoLog® Prescribing Information.

NovoLog® is a prescription medicine.

Talk to your doctor about the importance of diet and exercise in your treatment plan.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

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If you need assistance with prescription drug costs, help may be available. Visit pparx.org or call 1-888-4PPA-NOW.

Selected Important Safety Information

What are the possible side effects of NovoLog®?

• Low blood sugar, including when too much is taken. Some symptoms include sweating, shakiness, confusion, and headache. Severe low blood sugar can cause unconsciousness, seizures, and death.

• Other side effects include injection site reactions (like redness, swelling, and itching), skin thickening or pits at the injection site, swelling of your hands and feet, if taken with thiazolidinediones (TZDs) possible heart failure, vision changes, low potassium in your blood, and weight gain.

Please click here for additional Important Safety Information

The pump: A physicianʼs perspective
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Doctor knows best
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