Restrictionsapply
copayimage Restrictionsapply Save now
Planets Sun
Skip Navigation LinksHome > NovoLog® > How NovoLog® Works

How NovoLog® Works


NovoLog® can help you
maintain control

NovoLog® (insulin aspart [rDNA origin] injection) is used to treat both type 1 diabetes in patients 2 years and older, and type 2 diabetes. As an insulin therapy that you take at mealtime, NovoLog® is called a bolus insulin therapy.

Insulin therapy should mimic this natural pattern of how insulin is used in the body. Normally, the pancreas makes a small, steady flow of insulin, called a "basal" flow. This keeps blood sugar within a normal range overnight and between meals.

In a person who doesn't have diabetes, the pancreas makes a short burst, or "bolus," of insulin to handle the blood sugar from the meal. As a bolus, or fast-acting insulin, NovoLog® imitates these bursts, helping control mealtime blood sugar.

Basal insulin and NovoLog®

In addition to bolus insulin, there is basal insulin. In fact, you may already be taking a long-acting basal insulin.

In people without diabetes, a steady amount of bolus insulin is released into the bloodstream day and night. This insulin helps control blood sugar between meals and during sleep. Basal insulin and bolus insulin, such as NovoLog®, work together to control blood sugar.

NovoLog® vs regular human insulin

NovoLog® helps cover your mealtime insulin needs, when your blood sugar level rises quickly. As a fast-acting insulin analog, NovoLog® acts quickly, so you can eat within 5 to 10 minutes.

As you can see from the graph above, NovoLog® closely imitates the bodyʼs natural insulin response after eating. This can help you control your blood sugar. Learn more about types of insulin therapy.

Fast-acting mealtime insulin, like NovoLog®, lasts for 3 to 5 hours in your system. This means that NovoLog® may help you fit your insulin into your day. If you have an unpredictable mealtime schedule, NovoLog® can help you keep up.

With NovoLog®, you can work with your doctor to adjust your insulin dose for your own individual eating and exercise habits. You can also adjust for high or low blood glucose levels.

Indications and Usage

What is NovoLog® (insulin aspart [rDNA origin] injection)?

NovoLog® is a man-made insulin used to control high blood sugar in adults and children with diabetes mellitus.

Important Safety Information

Who should not use NovoLog®?

Do not use NovoLog® if your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients.

What should I tell my health care provider before taking NovoLog®?

About all of your medical conditions, including liver, kidney, or heart problems.
If you are pregnant, breastfeeding, or plan to do either.
About all prescription and nonprescription medicines you take, including supplements, as your dose may need to change.

How should I take NovoLog®?

Eat a meal within 5 to 10 minutes after using NovoLog®, a fast-acting insulin, to avoid low blood sugar. Do not inject NovoLog® if you do not plan to eat right after your injection or bolus pump infusion.
Do not mix NovoLog® with any other insulin when used in a pump or with any insulin other than NPH when used with injections by syringe.
Do not change your dose or type of insulin unless you are told to by your health care provider.
Do not share needles, insulin pens, or syringes.
Check your blood sugar levels as directed by your health care provider.

What should I consider while using NovoLog®?

Alcohol, including beer and wine, may affect your blood sugar.
Be careful when driving a car or operating machinery. You may have difficulty concentrating or reacting if you have low blood sugar. Talk to your health care provider if you often have low blood sugar or no warning signs of low blood sugar.

What are the possible side effects of NovoLog®?

Low blood sugar, including when too much is taken. Some symptoms include sweating, shakiness, confusion, and headache. Severe low blood sugar can cause unconsciousness, seizures, and death.
Serious allergic reactions may occur. Get medical help right away, if you develop a rash over your whole body, have trouble breathing, a fast heartbeat, or sweating.
Other side effects include injection site reactions (like redness, swelling, and itching), skin thickening or pits at the injection site, swelling of your hands and feet, if taken with thiazolidinediones (TZDs) possible heart failure, vision changes, low potassium in your blood, and weight gain.

For more information, please click here for complete NovoLog® Prescribing Information.

NovoLog® is a prescription medicine.

Talk to your doctor about the importance of diet and exercise in your treatment plan.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

PPA Logo Rev
If you need assistance with prescription drug costs, help may be available. Visit pparx.org or call 1-888-4PPA-NOW.

Selected Important Safety Information

What are the possible side effects of NovoLog®?

• Low blood sugar, including when too much is taken. Some symptoms include sweating, shakiness, confusion, and headache. Severe low blood sugar can cause unconsciousness, seizures, and death.

• Other side effects include injection site reactions (like redness, swelling, and itching), skin thickening or pits at the injection site, swelling of your hands and feet, if taken with thiazolidinediones (TZDs) possible heart failure, vision changes, low potassium in your blood, and weight gain.

Please click here for additional Important Safety Information

Doctor knows best
(2:19 min.)

Individual results may vary.

Email to a Friend:

email icon

To(;):

From:

Message: